FAU Advanced Health Assessment Practice Test

Acanthosis Nigricans is often associated with insulin resistance and hyperinsulinemia, making insulin stimulation a significant factor in its development. In conditions like obesity, type 2 diabetes, and metabolic syndrome, insulin levels can be elevated, which may lead to increased stimulation of epidermal growth factor receptors in the skin. This results in the characteristic thickening and darkening of the skin, particularly in body folds like the neck, armpits, and groin.

While hormonal imbalances can affect skin changes, and certain vitamin deficiencies or allergic reactions may lead to other dermatological conditions, they are less directly connected to Acanthosis Nigricans than the effects of insulin stimulation. Correctly identifying insulinemia as a causative factor highlights the role of metabolic processes in skin health and emphasizes the need for evaluating underlying conditions when recognizing such dermatologic signs.