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In Acanthosis Nigricans, which skin condition may exacerbate the symptoms?

  1. Friction

  2. Sun exposure

  3. Cold weather

  4. Dry skin

The correct answer is: Friction

Acanthosis Nigricans is characterized by dark, velvety patches of skin, often found in areas where skin rubs together, such as the neck, armpits, and groin. Friction can worsen the appearance and symptoms of Acanthosis Nigricans because the skin is more prone to irritation and thickening in areas that undergo repeated friction or rubbing. When friction occurs, it can lead to more pronounced skin changes and may exacerbate the overall condition, making it appear darker and more prominent. Sun exposure does not generally exacerbate Acanthosis Nigricans; in fact, the condition isn’t primarily influenced by UV rays. Cold weather might lead to dry skin, but it does not typically have a direct impact on Acanthosis Nigricans itself. Similarly, while dry skin can sometimes irritate certain skin conditions, it is not a direct exacerbating factor for Acanthosis Nigricans compared to the effects of friction. Thus, the role of friction in worsening the manifestations of Acanthosis Nigricans is clearly established, making it the most relevant option in this context.